1. Intentionally Lengthening Nonparetic Step Length Inhibits the Paretic-Side Swing-Phase Ankle Motion More than Knee Motion
Yuichi Tsushima,Kazuki Fujita,Koji Hayashi,Hiroichi Miaki Katsuhiro Hayashi
Biomechanics 2024, 4(2), 323-332; https://doi.org/10.3390/biomechanics4020022
2. Comparison of clinical outcome between surgical treatment and particle beam therapy for pelvic bone sarcomas: A retrospective multicenter study in Japan.
Toshiyuki Takemori, Hitomi Hara, Teruya Kawamoto, Naomasa Fukase, Ryoko Sawada, Shuichi Fujiwara, Ikuo Fujita, Takuya Fujimoto, Masayuki Morishita, Shunsuke Yahiro …
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2024年7月3日
3. Combination therapy with immune checkpoint inhibitors and denosumab improves clinical outcomes in non-small cell lung cancer with bone metastases.
Yohei Asano, Norio Yamamoto, Satoru Demura, Katsuhiro Hayashi, Akihiko Takeuchi, Satoshi Kato, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Yuta Taniguchi …
Lung cancer (Amsterdam, Netherlands) 193 107858-107858 2024年7月
4. Membrane Formed Around Liquid Nitrogen-treated Bone Promotes Osteogenesis and Revitalization in a Rat Model.
Yohei Asano, Norio Yamamoto, Katsuhiro Hayashi, Shinji Miwa, Takashi Higuchi, Yuta Taniguchi, Takayuki Nojima, Satoru Demura, Hiroyuki Tsuchiya
Anticancer research 44(7) 2887-2897 2024年7月
5. Pathology, Diagnosis, and Management of Sarcoma.
Shinji Miwa, Katsuhiro Hayashi, Satoru Demura
International journal of molecular sciences 25(12) 2024年6月15日
6. DNA-Binding Agent Trabectedin Combined With Recombinant Methioninase Is Synergistic to Decrease Fibrosarcoma Cell Viability and Induce Nuclear Fragmentation But Not Synergistic on Normal Fibroblasts.
Sei Morinaga, Qinghong Han, Yutaro Kubota, Kohei Mizuta, Byung Mo Kang, Motokazu Sato, Michael Bouvet, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura …
Anticancer research 44(6) 2359-2367 2024年6月
7. Combining dynamics of serum inflammatory and nutritional indicators as novel biomarkers in immune checkpoint inhibitor treatment of non-small-cell lung cancer with bone metastases.
Yohei Asano, Katsuhiro Hayashi, Akihiko Takeuchi, Satoshi Kato, Shinji Miwa, Yuta Taniguchi, Miho Okuda, Isao Matsumoto, Seiji Yano, Satoru Demura
International immunopharmacology 136 112276-112276 2024年5月30日
8. What are the Optimal Systemic Treatment Options for Rhabdomyosarcoma?
Shinji Miwa, Katsuhiro Hayashi, Yuta Taniguchi, Yohei Asano, Satoru Demura
Current treatment options in oncology 25(6) 784-797 2024年5月16日
9. Clinical features of patients with carcinoma soft tissue metastases as surgical indications: a retrospective cohort study.
Sei Morinaga, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Yohei Asano, Takayuki Nojima, Hiroyuki Tsuchiya
BMC cancer 24(1) 577-577 2024年5月10日
10. Development and validation of a nomogram to predict surgical site infection after soft-tissue sarcoma resection.
Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Yuta Taniguchi, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya
The bone & joint journal 106-B(5) 492-500 2024年5月1日
11. Intraoperative Fracture during the Insertion of Advanced Locking Screws (T2 Alpha Femur Retrograde Intramedullary Nailing System): Report of Two Cases and Identifying Causes and Prevention
Takashi Higuchi, Atsushi Taninaka, Rikuto Yoshimizu, Katsuhiro Hayashi, Shinji Miwa, Norio Yamamoto, Hiroyuki Tsuchiya, Satoru Demura
Journal of Clinical Medicine 13(8) 2024年4月19日
12. Tumor-induced Osteomalacia Successfully Treated by En Bloc Tumor Excision and Reconstruction Using a Tumor-bearing Frozen Autograft: A Case Report.
Martin Louie S Bangcoy, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Hideji Nishida, Akihiko Takeuchi, Kentaro Igarashi, Takashi Kato, Yuta Taniguchi, Sei Morinaga …
Anticancer research 44(4) 1791-1797 2024年4月
13. Extensive Synergy Between Recombinant Methioninase and Eribulin Against Fibrosarcoma Cells But Not Normal Fibroblasts
SEI MORINAGA, QINGHONG HAN, YUTARO KUBOTA, KOHEI MIZUTA, BYUNG MO KANG, MOTOKAZU SATO, MICHAEL BOUVET, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA …
Anticancer Research 44(3) 921-928 2024年2月29日
14. High Clinical Concordance of Drug Resistance in Patient-derived Orthotopic Xenograft (PDOX) Mouse Models: First Step to Validated Precise Individualized Cancer Chemotherapy
TAKASHI HIGUCHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, SHINJI MIWA, KENTARO IGARASHI, HIROYUKI TSUCHIYA, ROBERT M. HOFFMAN
Anticancer Research 43(10) 4277-4284 2023年9月29日
15. Graft Survivals after Reconstruction Using Tumor-Bearing Frozen Bone in the Extremities.
Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Martin Louie S Bangcoy, Yuta Taniguchi, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya
Cancers 15(15) 2023年8月2日
16. Needle tract seeding of a sclerosing epithelioid fibrosarcoma in a biopsy tract: a case report.
Masafumi Kawai, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Yuta Taniguchi, Yoshihiro Araki, Hirotaka Yonezawa, Takayuki Nojima …
BMC musculoskeletal disorders 24(1) 454-454 2023年6月3日
17. Novel predictors of immune checkpoint inhibitor response and prognosis in advanced non-small-cell lung cancer with bone metastasis.
Yohei Asano, Norio Yamamoto, Satoru Demura, Katsuhiro Hayashi, Akihiko Takeuchi, Satoshi Kato, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Yuta Taniguchi …
Cancer medicine 12(11) 12425-12437 2023年6月
18. A validation study for the utility of serum microRNA as a diagnostic and prognostic marker in patients with osteosarcoma.
Yoshihiro Araki, Naofumi Asano, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi …
Oncology letters 25(6) 222-222 2023年6月
19. Chondroprotective Effects of Chondrogenic Differentiated Adipose-Derived Mesenchymal Stem Cells Sheet on Degenerated Articular Cartilage in an Experimental Rabbit Model
Atsushi Taninaka, Tamon Kabata, Katsuhiro Hayashi, Yoshitomo Kajino, Daisuke Inoue, Takaaki Ohmori, Ken Ueoka, Yuki Yamamuro, Tomoyuki Kataoka, Yoshitomo Saiki …
Bioengineering 10(5) 574-574 2023年5月10日
20. Antibacterial effect and biological reaction of calcium phosphate cement impregnated with iodine for use in bone defects.
Sei Morinaga, Norio Yamamoto, Masaharu Tokoro, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Yohei Asano, Takayuki Nojima …
Journal of biomaterials applications 37(10) 1716-1723 2023年5月
21. Clinical Benefits of LigaSure™ for Surgical Amputation Without Tourniquet Use in Patients With Musculoskeletal Tumor.
Martin Louie S Bangcoy, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Yuta Taniguchi, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya
Anticancer research 43(5) 2127-2133 2023年5月
22. Outcomes of Window Therapy with Carboplatin and Ifosfamide for Pediatric Osteosarcoma: A Case Series.
Hisaki Aiba, Michi Kamei, Yasuhiko Ito, Risa Takeda, Satoshi Yamada, Hideki Okamoto, Katsuhiro Hayashi, Shinji Miwa, Yohei Kawaguchi, Shiro Saito …
Children (Basel, Switzerland) 10(4) 2023年4月17日
23. Combined adipose-derived mesenchymal stem cell and antibiotic therapy can effectively treat periprosthetic joint infection in rats.
Yuki Yamamuro, Tamon Kabata, Takayuki Nojima, Katsuhiro Hayashi, Masaharu Tokoro, Yoshitomo Kajino, Daisuke Inoue, Takaaki Ohmori, Junya Yoshitani, Takuro Ueno …
Scientific reports 13(1) 3949-3949 2023年3月9日
24. Case Report: Unresectable pulmonary metastases of a giant cell tumor of bone treated with denosumab: a case report and review of literature.
Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Yuta Taniguchi, Sei Morinaga, Yohei Asano, Takayuki Nojima, Hiroyuki Tsuchiya
Frontiers in oncology 13 1230074-1230074 2023年
25. Kimura's Disease Diagnosed in the Department of Orthopedic Surgery Treated With Wide Excision: Report of Two Cases.
Sei Morinaga, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Yohei Asano, Takayuki Nojima, Hiroyuki Tsuchiya
In vivo (Athens, Greece) 37(3) 1373-1378 2023年
26. The role of surgery in the treatment of metastatic bone tumor.
Hayashi K, Tsuchiya H.
Int J Clin Oncol (IF: 2.879; Q1). 2022 Aug;27(8):1238-1246. doi: 10.1007/s10147-022-02144-6. Epub 2022 Feb 28.
27. A nonsteroidal anti-inflammatory drug, zaltoprofen, inhibits the growth of extraskeletal chondrosarcoma cells by inducing PPARγ, p21, p27, and p53
Takashi Higuchi, Akihiko Takeuchi, Seiichi Munesue, Norio Yamamoto, Katsuhiro Hayashi, Ai Harashima, Yasuhiko Yamamoto, Hiroyuki Tsuchiya
Cell Cycle 1-12 2023年1月12日 (IF 5.173)
28. Bone Regeneration Using Autologous Adipose-Derived Stem Cell Spheroid Complex
Katsuhiro Hayashi, Xang Fang, Hiroshi Ueda, Akihiro Miwa, Toshiaki Naka, and Hiroyuki Tsuchiya
J. Biomater. Tissue Eng. 12, 1216–1223 (2022)
29. Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report.
Sei Morinaga, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Yohei Asano, Shiro Saito, Hiroyuki Tsuchiya
Journal of medical case reports 16(1) 436-436 2022年11月16日 (0)
30. A Viability Analysis of Tumor-Bearing Frozen Autograft for the Reconstruction After Resection of Malignant Bone Tumors Using 99mTc-MDP Scintigraphy.
Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Takayuki Nojima, Junichi Taki, Hiyoruki Tsuchiya
Clinical nuclear medicine 48(1) 25-34 2022年10月14日 (10.782)
31. Family cancer history and smoking habit associated with sarcoma in a Japanese population study.
Yoshihiro Araki, Norio Yamamoto, Yoshikazu Tanzawa, Takahiro Higashi, Aya Kuchiba, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Makoto Endo, Eisuke Kobayashi, Hiroyuki Tsuchiya, Akira Kawai
Scientific reports 12(1) 17129-17129 2022年10月12日 (4.996)
32. The Therapeutic Effect and Clinical Outcome of Immune Checkpoint Inhibitors on Bone Metastasis in Advanced Non-Small-Cell Lung Cancer.
Yohei Asano, Norio Yamamoto, Satoru Demura, Katsuhiro Hayashi, Akihiko Takeuchi, Satoshi Kato, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Shiro Saito, Takashi Sone, Kazuo Kasahara, Hiroyuki Tsuchiya
Frontiers in oncology 12 871675-871675 2022年 (5.738)
33. Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: The REALIZE study
Akihiko Takeuchi, Makoto Endo, Akira Kawai, Yoshihiro Nishida, Ryu Terauchi, Akihiko Matsumine, Hisaki Aiba, Tomoki Nakamura, Susumu Tandai, Toshifumi Ozaki, Manabu Hoshi, Daiki Kayano, Miho Okuda, Norio Yamamoto, Katsuhiro Hayashi, Shinji Miwa, Kentaro Igarashi, Kenichi Yoshimura, Akihiro Nomura, Toshinori Murayama, Hiroyuki Tsuchiya
Frontiers in Oncology 21 900010 2022年9月 (5.738)
34. Surgical Site Infection after Bone Tumor Surgery: Risk Factors and New Preventive Techniques
Shinji Miwa, Norio Yamamoto , Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Hiroyuki Tsuchiya
Cancers 14 4527 2022年９月 (6.575)
35. Clinical Outcomes of Limb-sparing Tumor Surgery With Vascular Reconstruction for Bone and Soft-tissue Tumors.
Yohei Asano, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Sei Morinaga, Kaoru Tada, Takayuki Nojima, Hiroyuki Tsuchiya
Anticancer research 42(9) 4619-4626 2022年9月 (2.435)
36. Do Liquid Nitrogen-treated Tumor-bearing Nerve Grafts Have the Capacity to Regenerate, and Do They Pose a Risk of Local Recurrence? A Study in Rats.
Hirotaka Yonezawa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Sei Morinaga, Yohei Asano, Shiro Saito, Kaoru Tada, Takayuki Nojima, Hiroyuki Tsuchiya
Clinical orthopaedics and related research 2022年8月19日 (3.85)
37. Clinical Outcome of Patients with Pelvic and Retroperitoneal Bone and Soft Tissue Sarcoma: A Retrospective Multicenter Study in Japan.
Toshiyuki Takemori, Teruya Kawamoto, Hitomi Hara, Naomasa Fukase, Shuichi Fujiwara, Ikuo Fujita, Takuya Fujimoto, Masayuki Morishita, Kazumichi Kitayama, Shunsuke Yahiro, Tomohiro Miyamoto, Masanori Saito, Jun Sugaya, Katsuhiro Hayashi, Hiroyuki Kawashima, Tomoaki Torigoe, Tomoki Nakamura, Hiroya Kondo, Toru Wakamatsu, Munenori Watanuki, Munehisa Kito, Satoshi Tsukushi, Akihito Nagano, Hidetatsu Outani, Shunichi Toki, Shunji Nishimura, Hiroshi Kobayashi, Itsuo Watanabe, Yusuke Demizu, Ryohei Sasaki, Takumi Fukumoto, Takahiro Niikura, Ryosuke Kuroda, Toshihiro Akisue
Cancers 14(12) 2022年6月20日 (6.575)
38. Compartment-specific Clinical Outcomes in Patients With Soft Tissue Sarcomas of the Thigh.
Sei Morinaga, Akihiko Takeuchi, Norio Yamamoto, Katsuhiro Hayashi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Yohei Asano, Shiro Saito, Takayuki Nojima, Hiroyuki Tsuchiya
Anticancer research 42(6) 3143-3150 2022年6月 (2.435)
39. Treatment of infected calcific myonecrosis with chronically discharging sinus caused by iatrogenic aspiration: A case report.
Takashi Higuchi, Norio Yamamoto, Hideji Nishida, Katsuhiro Hayashi, Akihiko Takeuchi, Hiroyuki Tsuchiya
International journal of surgery case reports 95 107145-107145 2022年5月6日 (0)
40. Dedifferentiated chondrosarcoma of the middle finger arising from a solitary enchondroma: A case report
Hirotaka Yonezawa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Sei Morinaga, Yohei Asano, Shiro Saito, Yasunori Tome, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya
World Journal of Clinical Cases 10(10) 3297-3305 2022年4月6日 (1.534)
41. Pretreatment Neutrophil Count and Platelet-lymphocyte Ratio as Predictors of Metastasis in Patients With Osteosarcoma.
Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya
Anticancer research 42(2) 1081-1089 2022年2月 (2.435)
42. Primary total knee arthroplasty assisted by computed tomography-free navigation for secondary knee osteoarthritis following massive calcium phosphate cement packing for distal femoral giant-cell bone tumor treatment: a case report.
Akihiko Takeuchi, Norio Yamamoto, Takaaki Ohmori, Katsuhiro Hayashi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Hirotaka Yonezawa, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Shiro Saito, Hiroyuki Tsuchiya
BMC musculoskeletal disorders 23(1) 170-170 2022年2月22日 (2.562)
43. Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application.
Takashi Higuchi, Kentaro Igarashi, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Michael Bouvet, Hiroyuki Tsuchiya, Robert M Hoffman
Frontiers in oncology 12 957844-957844 2022年 (5.738)
44. A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma.
Yohei Asano, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Takayuki Nojima, Hiroko Ikeda, Hiroyuki Tsuchiya
Scientific reports 12(1) 237-237 2022年1月7日 (4.996)
45. Impact of Tumor Growth Speed of Primary Lesions on the Clinical Outcomes of Appendicular Skeletal Metastases.
Yohei Asano, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Shiro Saito, Takayuki Nojima, Hiroyuki Tsuchiya
Anticancer research 42(1) 229-236 2022年1月 (2.435)
46. Takashi Higuchi, Kentaro Igarashi, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Michael Bouvet, Hiroyuki Tsuchiya, Robert M Hoffman. Osteosarcoma Patient-derived Orthotopic Xenograft (PDOX) Models Used to Identify Novel and Effective Therapeutics: A Review. Anticancer research 41(12): 5865-5871, 2021年12月.
47. So-Ichiro Sasaki, Di Zhang, Sadahiro Iwabuchi, Yamato Tanabe, Shinichi Hashimoto, Akira Yamauchi, Katsuhiro Hayashi, Hiroyuki Tsuchiya, Yoshihiro Hayakawa, Tomohisa Baba, Naofumi Mukaida. Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation. Cancer science 112(12): 4883-4893, 2021年10月10日.
48. Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya. Clinical outcomes of frozen autograft reconstruction for the treatment of primary bone sarcoma in adolescents and young adults. Scientific reports 11(1): 17291-17291, 2021年8月27日.
49. S Miwa, T Nojima, A A Alomesen, H Ikeda, N Yamamoto, H Nishida, K Hayashi, A Takeuchi, K Igarashi, T Higuchi, H Yonezawa, Y Araki, S Morinaga, Y Asano, H Tsuchiya. Associations of PD-L1, PD-L2, and HLA class I expression with responses to immunotherapy in patients with advanced sarcoma: post hoc analysis of a phase 1/2 trial. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 23(8): 1620-1629, 2021年8月.
50. Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Hirotaka Yonezawa, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Shiro Saito, Miho Okuda, Junichi Taki, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. A Radiological Scoring System for Differentiation between Enchondroma and Chondrosarcoma. Cancers 13(14):, 2021年7月16日.
51. Gang Xu, Hisaki Aiba, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Yoshihiro Araki, Shiro Saito, Kenichi Yoshimura, Hideki Murakami, Hiroyuki Tsuchiya, Akira Kawai. Efficacy of perioperative chemotherapy for synovial sarcoma: a retrospective analysis of a Nationwide database in Japan. BMC cancer 21(1): 773-773, 2021年7月3日.
52. Katsuhiro Hayashi, Koji Hiraoka, Toru Akiyama*, Shintaro Iwata, Hiroyuki Tsuchiya, Akira Kawai. Benefit of surgical resection of distant metastasis in soft tissue sarcoma: a systematic review. Japanese journal of clinical oncology 51(7): 1088-1093, 2021年7月1日.
53. Hirotaka Yonezawa, Katsuhiro Hayashi, Norio Yamamoto, Akihiko Takeuchi, Kaoru Tada, Shinji Miwa, Kentaro Igarashi, Hiroaki Kimura, Yu Aoki, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Keisuke Sakurakichi, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. Significant Improvement After Surgery for a Symptomatic Osteoblastoma in a Patient with Camurati-Engelmann Disease: Case Report and Literature Review. Calcified tissue international 108(6): 819-824, 2021年6月.
54. Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya. Delayed Initiation of Treatment Is Associated With Metastasis of Malignant Bone Tumor. Anticancer research 41(6): 2993-2999, 2021年6月.
55. Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. Author Correction: The number of osteoclasts in a biopsy specimen can predict the efficacy of neoadjuvant chemotherapy for primary osteosarcoma. Scientific reports 11(1): 8831-8831, 2021年4月19日.
56. Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Takashi Higuchi, Hirotaka Yonezawa, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. Diagnostic accuracies of intraoperative frozen section and permanent section examinations for histological grades during open biopsy of bone tumors. International journal of clinical oncology 26(3): 613-619, 2021年3月.
57. Yohei Asano, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Kazuo Kasahara, Takashi Sone, Hiroyuki Tsuchiya. Complete Response of Bone Metastasis in Non-small Cell Lung Cancer With Pembrolizumab: Two Case Reports. Anticancer research 41(3): 1693-1699, 2021年3月.
58. Katsuhiro Hayashi*, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yoshihiro Araki, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya. Long-term survival in a patient with Hutchinson-Gilford progeria syndrome and osteosarcoma: A case report. World journal of clinical cases 9(4): 854-863, 2021年2月6日.
59. Yoshihiro Araki, Katsuhiro Hayashi, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Takayuki Nojima, Hiroyuki Tsuchiya. Reconstruction using a frozen autograft for a skull and humeral lesion of synchronous multicentric osteosarcoma after undergoing successful neoadjuvant chemotherapy: a case report and review of the literature. BMC surgery 21(1): 56-56, 2021年1月22日.
60. Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. The number of osteoclasts in a biopsy specimen can predict the efficacy of neoadjuvant chemotherapy for primary osteosarcoma. Scientific reports 11(1): 1989-1989, 2021年1月21日.
61. Yoshihiro Araki, Hisaki Aiba, Takeshi Yoshida, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Tuan D Nguyen, Kiyo-Aki Ishii, Takayuki Nojima, Satoru Takahashi, Hideki Murakami, Hiroyuki Tsuchiya, Rikinari Hanayama. Osteosarcoma-Derived Small Extracellular Vesicles Enhance Tumor Metastasis and Suppress Osteoclastogenesis by miR-146a-5p. Frontiers in oncology 11: 667109-667109, 2021年.
62. Hisaki Aiba, Hiroaki Kimura, Satoshi Yamada, Hideki Okamoto, Katsuhiro Hayashi, Shinji Miwa, Yohei Kawaguchi, Shiro Saito, Takao Sakai, Tsutomu Tatematsu, Ryoichi Nakanishi, Hideki Murakami. Different patterns of pneumothorax in patients with soft tissue tumors treated with pazopanib: A case series analysis. PloS one 16(7): e0254866, 2021年.
63. Kaoru Tada, Mika Nakada, Masashi Matsuta, Atsuro Murai, Katsuhiro Hayashi, Hiroyuki Tsuchiya. Enhanced nerve autograft using stromal vascular fraction. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie 31(1) 183-188 2021年1月
64. Hirotaka Yonezawa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Mickhael Bang Langit, Hiroaki Kimura, Shingo Shimozaki, Takashi Kato, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. Low-grade myofibroblastic sarcoma of the levator scapulae muscle: a case report and literature review. BMC musculoskeletal disorders 21(1): 836-836, 2020.
65. Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Higuchi Takashi, Abe Kensaku, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya. Delayed Initiation of Treatment Is Associated With Metastasis of Soft-tissue Sarcoma. Anticancer research 40(12): 7009-7015, 2020.
66. Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Takashi Higuchi, Hirotaka Yonezawa, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya. Accuracy of histological grades from intraoperative frozen-section diagnoses of soft-tissue tumors. International journal of clinical oncology 25(12): 2158-2165, 2020.
67. Akihiko Takeuchi, Norio Yamamoto, Katsuhiro Hayashi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Hiroko Ikeda, Hiroyuki Tsuchiya. Intraoperative ultrasonography-guided surgery for malignant soft tissue tumor. Journal of surgical oncology 122(8): 1791-1801, 2020.
68. Gang Xu, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Yoshihiro Araki, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya. Atypical and incomplete pulmonary hypertrophic osteoarthropathy in the left distal femur: a case report. BMC surgery 20(1): 293-293, 2020.
69. Kensaku Abe, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Yuta Taniguchi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya. Diagnosis and treatment of intramedullary osteosclerosis: a report of three cases and literature review. BMC musculoskeletal disorders 21(1): 762-762, 2020.
70. Hirotaka Yonezawa, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Mickhael B Langit, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Hiroyuki Tsuchiya. Structural Origin and Surgical Complications of Peripheral Schwannomas. Anticancer research 40(11): 6563-6570, 2020.
71. Tomoharu Takagi, Tamon Kabata, Katsuhiro Hayashi, Xiang Fang, Yoshitomo Kajino, Daisuke Inoue, Takaaki Ohmori, Takuro Ueno, Junya Yoshitani, Ken Ueoka, Yuki Yamamuro, Hiroyuki Tsuchiya. Periodic injections of adipose-derived stem cell sheets attenuate osteoarthritis progression in an experimental rabbit model. BMC musculoskeletal disorders 21(1): 691-691, 2020.
72. Takashi Higuchi, Norihiko Sugisawa, Jun Ho Park, Yu Sun, Guangwei Zhu, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M Hoffman. Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival. Translational oncology 13(10): 100826-100826, 2020.
73. Katsuhiro Hayashi*, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hisaki Aiba, Yoshihiro Araki, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya. Clinical course of grafted cartilage in osteoarticular frozen autografts for reconstruction after resection of malignant bone and soft-tissue tumor involving an epiphysis. Journal of bone oncology 24: 100310-100310, 2020.
74. Shiro Saito, Hisaki Aiba, Satoshi Yamada, Hideki Okamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Takanobu Otsuka, Hideki Murakami. Efficacy of combination-chemotherapy with pirarubicin, ifosfamide, and etoposide for soft tissue sarcoma: a single-institution retrospective analysis. BMC cancer 20(1): 868-868, 2020.
75. Kentaro Igarashi, Norio Yamamoto, Katsuhiro Hayashi, Hidenori Matsubara, Akihiko Takeuchi, Shinji Miwa, Hiroyuki Tsuchiya. Distal Tibial Tuberosity Focal Dome Osteotomy Combined With Intra-Articular Condylar Osteotomy (Focal Dome Condylar Osteotomy) for Medial Osteoarthritis of the Knee Joint. Arthroscopy techniques 9(8): e1079-e1086, 2020.
76. Junya Yoshitani, Tamon Kabata, Hiroshi Arakawa, Yukio Kato, Takayuki Nojima, Katsuhiro Hayashi, Masaharu Tokoro, Naotoshi Sugimoto, Yoshitomo Kajino, Daisuke Inoue, Ken Ueoka, Yuki Yamamuro, Hiroyuki Tsuchiya. Combinational therapy with antibiotics and antibiotic-loaded adipose-derived stem cells reduce abscess formation in implant-related infection in rats. Scientific reports 10(1): 11182-11182, 2020.
77. Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Hiroyuki Tsuchiya. Recent Advances and Challenges in the Treatment of Rhabdomyosarcoma. Cancers 12(7):, 2020.
78. Daiki Yamamoto, Kaoru Tada, Seigo Suganuma, Katsuhiro Hayashi, Tadahiro Nakajima, Mika Nakada, Masashi Matsuta, Hiroyuki Tsuchiya. Differentiated adipose-derived stem cells promote peripheral nerve regeneration. Muscle & nerve 62(1): 119-127, 2020.
79. Mickhael Bang Langit, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Takashi Higuchi, Hirotaka Yonezawa, Sei Morinaga, Yoshihiro Araki, Yohei Asano, Hiroyuki Tsuchiya. Risk Factors for Postoperative Deep Infection After Malignant Bone Tumor Surgery of the Extremities. Anticancer research 40(6): 3551-3557, 2020.
80. Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Takayuki Nojima, Hiroyuki Tsuchiya. Cystic extraskeletal osteosarcoma: Three case reports and review of the literature. Molecular and clinical oncology 12(5): 468-474, 2020.
81. Kentaro Igarashi, Kei Kawaguchi, Ming Zhao, Qinghong Han, Yuying Tan, Tasuku Kiyuna, Kentaro Miyake, Takashi Higuchi, Scott D Nelson, Sarah M Dry, Yunfeng Li, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M Hoffman. Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma. Anticancer research 40(5): 2515-2523, 2020.
82. Takashi Higuchi, Qinghong Han, Kentaro Miyake, Hiromichi Oshiro, Norihiko Sugisawa, Yuying Tan, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M Hoffman. Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model. Biochemical and biophysical research communications 523(1): 135-139, 2020.
83. Gang Xu, Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Takashi Higuchi, Yuta Taniguchi, Yoshihiro Araki, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya. Pedicle frozen autograft-prosthesis composite reconstructions for malignant bone tumors of the proximal femur. BMC musculoskeletal disorders 21(1): 81-81, 2020.
84. Gang Xu, Norio Yamamoto, Takayuki Nojima, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hiroyuki Tsuchiya. The process of bone regeneration from devitalization to revitalization after pedicle freezing with immunohistochemical and histological examination in rabbits. Cryobiology 92: 130-137, 2020.
85. Kentaro Igarashi, Kei Kawaguchi, Ming Zhao, Tasuku Kiyuna, Kentaro Miyake, Masuyo Miyake, Scott D Nelson, Sarah M Dry, Yunfeng Li, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Takashi Higuchi, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M Hoffman. Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model. Translational oncology 13(2): 393-400, 2020.
86. Higuchi T, Sugisawa N, Yamamoto J, Oshiro H, Han Q, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Tan Y, Kuchipudi S, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model. Cancer chemotherapy and pharmacology 85(2): 285-291, 2020.
87. Kensaku Abe, Norio Yamamoto, Takahiro Domoto, Dilireba Bolidong, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hiroyuki Inatani, Yu Aoki, Takashi Higuchi, Yuta Taniguchi, Hirotaka Yonezawa, Yoshihiro Araki, Hisaki Aiba, Toshinari Minamoto, Hiroyuki Tsuchiya. Glycogen synthase kinase 3β as a potential therapeutic target in synovial sarcoma and fibrosarcoma. Cancer science 111(2): 429-440, 2020.
88. Kentaro Igarashi, Kei Kawaguchi, Takashi Murakami, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Yukihiko Hiroshima, Takashi Higuchi, Hiromichi Oshiro, Scott D Nelson, Sarah M Dry, Yunfeng Li, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M Hoffman. Patient-derived orthotopic xenograft models of sarcoma. Cancer letters 469: 332-339, 2020.
89. Atsuro Murai, Kaoru Tada, Mika Nakada, Masashi Matsuta, Katsuhiro Hayashi, Hiroyuki Tsuchiya. Use of a Free Vascularized Medial Femoral Condyle Flap for Revision Surgery in a Pediatric Patient with Congenital Pseudarthrosis of the Clavicle. Case reports in orthopedics 2020: 8872934-8872934, 2020.
90. Takashi Higuchi, Jun Yamamoto, Norihiko Sugisawa, Yoshihiko Tashiro, Hiroto Nishino, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M. Hoffman. PPAR gamma Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model CANCER GENOMICS & PROTEOMICS 17(1): 35-40, 2020.
91. Aiba H, Hayashi K*, Yamada S, Okamoto H, Kimura H, Miwa S, Inatani H, Otsuka T, Murakami H. Treatment of a Malignant Soft Tissue Tumor Arising in the Vicinity of the Sciatic Nerve with an In-Situ Preparation Technique and Intensive Multidisciplinary Therapy. Cancers (Basel). 2019 Apr 10;11(4). pii: E506. doi: 10.3390/cancers11040506.
92. Aiba H, Yamada S, Mizutani J, Yamamoto N, Okamoto H, Hayashi K, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Tsuchiya H and Otsuka T: Efficacy of radio-hyperthermo-chemotherapy as salvage therapy for recurrent or residual malignant soft tissue tumors. Int J Hyperth 35: 658–666, 2019.
93. Shirai T, Tsuchiya H, Terauchi R, Tsuchida S, Mizoshiri N, Mori Y, Takeuchi A, Hayashi K, Yamamoto N, Ikoma K, Kubo T. A retrospective study of antibacterial iodine-coated implants for postoperative infection. Medicine (Baltimore). 2019 Nov;98(45):e17932. doi: 10.1097/MD.0000000000017932.
94. Taniguchi Y, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Higuchi T, Abe K, Yonezawa H, Araki Y, Morinaga S, Kamei J, Nugroho AE, Kaneda T, Morita H, Tsuchiya H. Anti-tumor Effects of Cyclolinopeptide on Giant-cell Tumor of the Bone. Anticancer Res. 2019 Nov;39(11):6145-6153. doi: 10.21873/anticanres.13822.
95. Takeuchi A, Yamamoto N, Hayashi K, Matsubara H, Miwa S, Igarashi K, Tsuchiya H. Joint-preservation surgery for pediatric osteosarcoma of the knee joint. Cancer Metastasis Rev. 2019 Dec;38(4):709-722. doi: 10.1007/s10555-019-09835-z.
96. Xu G, Yamamoto N, Nojima T, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Tsuchiya H. The process of bone regeneration from devitalization to revitalization after pedicle freezing with immunohistochemical and histological examination in rabbits. Cryobiology. 2019 Dec 22. pii: S0011-2240(19)30289-5. doi: 10.1016/j.cryobiol.2019.12.002
97. Yoshida Y, Matsubara H, Fang X, Hayashi K, Nomura I, Ugaji S, Hamada T, Tsuchiya H. Adipose-derived stem cell sheets accelerate bone healing in rat femoral defects. PLoS One. 2019 Mar 28;14(3):e0214488. doi: 10.1371/journal.pone.0214488. eCollection 2019.
98. Aoki Y, Yamamoto N, Hayashi K, Sugimoto N, Kimura H, Takeuchi A, Miwa S, Igarashi K, Inatani H, Higuchi T, Abe K, Taniguchi Y, Araki Y, Tsuchiya H. Revitalization of frozen autologous bone graft using adipose-derived stem cells. J Transl Sci 5:1-7, 2019
99. Yamamoto N, Hayashi K, Tsuchiya H. Progress in biological reconstruction and enhanced bone revitalization for bone defects. J Orthop Sci. 2019 Feb 20. pii: S0949-2658(19)30054-5. doi: 10.1016/j.jos.2019.01.015.
100. Miwa S, Shirai T, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tsuchiya H. Current and Emerging Targets in Immunotherapy for Osteosarcoma. J Oncol. 2019 Jan 1;2019:7035045. doi: 10.1155/2019/7035045. eCollection 2019.
101. Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tsuchiya H. Therapeutic Targets for Bone and Soft-Tissue Sarcomas. Int J Mol Sci. 2019 Jan 4;20(1). pii: E170. doi: 10.3390/ijms20010170. Review.
102. Zekry KM, Yamamoto N, Hayashi K, Takeuchi A, Araki Y, Alkhooly AZA, Abd-Elfattah AS, Fouly EH, Elsaid ANS, Tsuchiya H. Surgical treatment of chondroblastoma using extended intralesional curettage with phenol as a local adjuvant. J Orthop Surg (Hong Kong). 2019 Sep-Dec;27(3):2309499019861031. doi: 10.1177/2309499019861031.
103. Abe K, Yamamoto N, Hayashi K, Takeuchi A, Kato S, Miwa S, Igarashi K, Inatani H, Aoki YU, Higuchi T, Taniguchi Y, Tsuchiya H. Satisfaction After Joint-preservation Surgery in Patients With Musculoskeletal Knee Sarcoma Based on Various Scores. Anticancer Res. 2019 Apr;39(4):1959-1964. doi: 10.21873/anticanres.13306.
104. Abe K, Yamamoto N, Hayashi K, Takeuchi A, Kato S, Miwa S, Igarashi K, Inatani H, Aoki YU, Higuchi T, Taniguchi Y, Tsuchiya H. Determining Patient Satisfaction and Treatment Desires in Patients With Musculoskeletal Sarcoma of the Knee After Joint-preservation Surgery Using a Questionnaire Survey. Anticancer Res. 2019 Apr;39(4):1965-1969. doi: 10.21873/anticanres.13307.
105. Higuchi T, Yamamoto N, Hayashi K, Takeuchi A, Abe K, Taniguchi Y, Araki Y, Tsuchiya H. C-arm cone-beam computed tomography-guided minimally invasive open excision of an osteoid osteoma undetectable on fluoroscopy: A case report. Int J Surg Case Rep. 2019;61:14-19. doi: 10.1016/j.ijscr.2019.06.062. Epub 2019 Jul 8.
106. Zekry KM, Yamamoto N, Hayashi K, Takeuchi A, Alkhooly AZA, Abd-Elfattah AS, Elsaid ANS, Ahmed AR, Tsuchiya H. Reconstruction of intercalary bone defect after resection of malignant bone tumor. J Orthop Surg (Hong Kong). 2019 Jan-Apr;27(1):2309499019832970. doi: 10.1177/2309499019832970.
107. Abe K, Yamamoto N, Hayashi K, Takeuchi A, Tsuchiya H. Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo. Abe K, Yamamoto N, Hayashi K, Takeuchi A, Tsuchiya H. BMC Cancer. 2019 Jul 15;19(1):689. doi: 10.1186/s12885-019-5891-y.
108. Takeuchi A, Matsubara H, Yamamoto N, Hayashi K, Miwa S, Igarashi K, Inatani H, Tsuchiya H. Successful treatment of pathologic femoral shaft fracture associated with large arteriovenous malformations using a 3-dimensional external fixator and teriparatide: a case report. BMC Surg. 2019 Apr 5;19(1):35. doi: 10.1186/s12893-019-0498-4.
109. Takeuchi A, Nomura A, Yamamoto N, Hayashi K, Igarashi K, Tandai S, Kawai A, Matsumine A, Miwa S, Nishida Y, Nakamura T, Terauchi R, Hoshi M, Kunisada T, Endo M, Yoshimura K, Murayama T, Tsuchiya H. Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: a study protocol. BMC Musculoskelet Disord. 2019 Feb 9;20(1):68. doi: 10.1186/s12891-019-2453-z.
110. Miwa S, Shirai T, Yamamoto N, Hayashi K, Takeuchi A, Tada K, Kajino Y, Higuchi T, Abe K, Aiba H, Taniguchi Y, Tsuchiya H. Risk factors for surgical site infection after malignant bone tumor resection and reconstruction. BMC Cancer. 2019 Jan 8;19(1):33. doi: 10.1186/s12885-019-5270-8.
111. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model. Transl Oncol. 2019 Sep;12(9):1257-1263. doi: 10.1016/j.tranon.2019.06.002. Epub 2019 Jul 9.
112. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Kline Z, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression. Biomed Pharmacother. 2019 Oct;118:109356. doi: 10.1016/j.biopha.2019.109356. Epub 2019 Aug 22.
113. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Kline Z, Belt P, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model. Anticancer Res. 2019 Sep;39(9):4781-4786. doi: 10.21873/anticanres.13662.
114. Higuchi T, Oshiro H, Miyake K, Sugisawa N, Han Q, Tan Y, Park J, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Chawla SP, Singh SR, Tsuchiya H, Hoffman RM. Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma. Anticancer Res. 2019 Sep;39(9):4653-4657. doi: 10.21873/anticanres.13646.
115. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model. Anticancer Res. 2019 Aug;39(8):4079-4084. doi: 10.21873/anticanres.13565.
116. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh SR, Tsuchiya H, Hoffman RM. Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model. Tissue Cell. 2019 Jun;58:107-111. doi: 10.1016/j.tice.2019.04.010. Epub 2019 May 3.
117. Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model. Cancer Chemother Pharmacol. 2019 Jun;83(6):1075-1082. doi: 10.1007/s00280-019-03824-3. Epub 2019 Mar 30.
118. Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model. Cancer Lett. 2019 Jun 1;451:122-127. doi: 10.1016/j.canlet.2019.03.003. Epub 2019 Mar 10.
119. Higuchi T, Miyake K, Oshiro H, Sugisawa N, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model. Biochem Biophys Res Commun. 2019 May 28;513(2):326-331. doi: 10.1016/j.bbrc.2019.03.191. Epub 2019 Apr 5.
120. Higuchi T, Oshiro H, Zhang Z, Miyake K, Sugisawa N, Katsuya Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Zhao M, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice. Transl Oncol. 2019 Apr;12(4):640-645. doi: 10.1016/j.tranon.2019.01.007. Epub 2019 Feb 23.
121. Higuchi T, Kawaguchi K, Miyake K, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Nelson SD, Dry SM, Li Y, Chawla SP, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM. The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Biomed Pharmacother. 2019 Mar;111:835-840. doi: 10.1016/j.biopha.2018.12.110. Epub 2019 Jan 4.
122. Hayashi K*, Yahata T, Muramoto R, Yamamoto N, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Aiba H, Araki Y, Tsuchiya H. Factors Associated with Discharge Destination in Advanced Cancer Patients with Bone Metastasis in a Japanese Hospital. Ann Rehabil Med, 2018;42(3):477-482.
123. Zekry KM, Yamamoto N, Hayashi K, Takeuchi A and Tsuchiya H: Primary Lymphoma of the Pelvis: A Case Report. J Orthop case reports 7: 6–9,2018
124. MIWA S, MOCHIZUKI T, YAMAMOTO N, SHIRAI T, HAYASHI K, TAKEUCHI A, INATANI H, IGARASHI K, HIGUCHI T, ABE K, TANIGUCHI Y, AIBA H, IKEDA H and TSUCHIYA H: Efficacy and Limitations of F-18-fluoro-2-deoxy-D-glucose Positron Emission Tomography to Differentiate Between Malignant and Benign Bone and Soft Tissue Tumors. Anticancer Res 38: 4065–4072, 2018.
125. Higuchi T, Yamamoto N, Hayashi K, Takeuchi A, Abe K, Taniguchi Y, Kato S, Murakami H and Tsuchiya H: Long-term patient survival after the surgical treatment of bone and soft-tissue metastases from renal cell carcinoma. Bone Joint J 100–B: 1241–1248, 2018.
126. HIGUCHI T, KAWAGUCHI K, MIYAKE K, HAN Q, TAN Y, OSHIRO H, SUGISAWA N, ZHANG Z, RAZMJOOEI S, YAMAMOTO N, HAYASHI K, KIMURA H, MIWA S, IGARASHI K, CHAWLA SP, SINGH AS, EILBER FC, SINGH SR, TSUCHIYA H and HOFFMAN RM: Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model. Anticancer Res 38: 5639–5644, 2018.
127. Zekry KM, Yamamoto N, Hayashi K, Takeuchi A, Alkhooly AZAA, Abd-Elfattah AS, Fouly EH, Ahmed AR and Tsuchiya H: Treatment of the benign lytic lesions of the proximal femur with synthetic bone graft. J Orthop Surg Res 13: 270, 2018.
128. Aiba H, Yamada S, Mizutani J, Yamamoto N, Okamoto H, Hayashi K, Kimura H, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Araki Y, Tsuchiya H and Otsuka T: Preoperative evaluation of the efficacy of radio-hyperthermo-chemotherapy for soft tissue sarcoma in a case series. PLoS One 13: e0195289, 2018.
129. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li S, Han Q, Tan Y, Zhao M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC and Hoffman RM: Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic. Cell Cycle 17: 801–809, 2018.
130. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC and Hoffman RM: Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model. Oncotarget 9: 7774–7781, 2018.
131. Higuchi T, Yamamoto N, Hayashi K, Takeuchi A, Kato S, Miwa S, Abe K, Taniguchi Y, Aiba H and Tsuchiya H: The Efficacy of Wide Resection for Musculoskeletal Metastatic Lesions of Renal Cell Carcinoma. Anticancer Res 38: 577–582, 2018.
132. Aiba H, Yamada S, Yamamoto N, Hayashi K, Miwa S, Tsuchiya H and Otsuka T: Spontaneous shrinkage of solitary osteochondromas. Skeletal Radiol 47: 61–68, 2018.
133. Higuchi T, Yamamoto N, Hayashi K, Takeuchi A, Abe K, Taniguchi Y, Araki Y, Tada K and Tsuchiya H: Successful joint preservation of distal radius osteosarcoma by en bloc tumor excision and reconstruction using a tumor bearing frozen autograft: a case report. BMC Surg 18: 12, 2018.
134. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Singh SR, Eilber FC and Hoffman RM: Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models. Biochem Biophys Res Commun 497: 1055–1061, 2018.
135. Igarashi K, Kawaguchi K, Li S, Han Q, Tan Y, Murakami T, Kiyuna T, Miyake K, Miyake M, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Singh SR, Eilber FC and Hoffman RM: Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma. Cancer Lett 417: 168–173, 2018.
136. Igarashi K, Kawaguchi K, Li S, Han Q, Tan Y, Gainor E, Kiyuna T, Miyake K, Miyake M, Higuchi T, Oshiro H, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC and Hoffman RM: Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model. Oncotarget 9: 19263–19272, 2018.
137. Aiba H, Yamada S, Mizutani J, Yamamoto N, Okamoto H, Hayashi K, Kimura H, Takeuchi A, Miwa S, Kawai A, Yoshimura K, Tsuchiya H and Otsuka T: Clinical outcomes of radio-hyperthermo-chemotherapy for soft tissue sarcoma compared to a soft tissue sarcoma registry in Japan: a retrospective matched-pair cohort study. Cancer Med 7: 1560–1571, 2018.
138. Igarashi K, Li S, Han Q, Tan Y, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC and Hoffman RM: Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase. J Cell Biochem 119: 3537–3544, 2018.
139. Higuchi T, Yamamoto N, Shirai T, Hayashi K, Takeuchi A, Kimura H, Miwa S, Abe K, Taniguchi Y and Tsuchiya H: Treatment outcomes of the simple bone cyst: A comparative study of 2 surgical techniques using artificial bone substitutes. Medicine (Baltimore) 97: e0572, 2018.
140. Higuchi T, Yamamoto N, Hayashi K, Takeuchi A, Kimura H, Miwa S, Igarashi K, Abe K, Taniguchi Y, Aiba H and Tsuchiya H: Calcium Phosphate Cement in the Surgical Management of Benign Bone Tumors. Anticancer Res 38: 3031–3035, 2018.
141. Higuchi T, Takeuchi A, Munesue S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Inatani H, Shimozaki S, Kato T, Aoki Y, Abe K, Taniguchi Y, Aiba H, Murakami H, Harashima A, Yamamoto Y and Tsuchiya H: Anti-tumor effects of a nonsteroidal anti-inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator-activated receptor gamma and suppressing matrix metalloproteinase-2 expression. Cancer Med 7: 1944–1954, 2018.
142. Takeuchi A, Suwanpramote P, Yamamoto N, Shirai T, Hayashi K, Kimura H, Miwa S, Higuchi T, Abe K and Tsuchiya H: Mid- to long-term clinical outcome of giant cell tumor of bone treated with calcium phosphate cement following thorough curettage and phenolization. J Surg Oncol 117: 1232–1238, 2018.
143. Takeuchi A, Yamamoto N, Hayashi K, Matsubara H, Kimura H, Miwa S, Higuchi T, Abe K, Taniguchi Y and Tsuchiya H: Growth of epiphysis after epiphyseal-preservation surgery for childhood osteosarcoma around the knee joint. BMC Musculoskelet Disord 19: 185, 2018.
144. Miwa S, Mochizuki T, Yamamoto N, Shirai T, Hayashi K, Takeuchi A, Inatani H, Igarashi K, Higuchi T, Abe K, Taniguchi Y, Aiba H, Ikeda H and Tsuchiya H: Efficacy and Limitations of F-18-fluoro-2-deoxy-D-glucose Positron Emission Tomography to Differentiate Between Malignant and Benign Bone and Soft Tissue Tumors. Anticancer Res 38: 4065–4072, 2018.
145. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC and Hoffman RM: Temozolomide regresses a doxorubicin-resistant undifferentiated spindle-cell sarcoma patient-derived orthotopic xenograft (PDOX): precision-oncology nude-mouse model matching the patient with effective therapy. J Cell Biochem 119: 6598–6603, 2018.
146. Hayashi K*, Yamamoto N, Shirai T, Takeuchi A, Kimura H, Miwa S, Higuchi T, Abe K, Taniguchi Y, Aiba H, Kiyohara H, Imai R, Ikeda H, Tsuchiya H. Sequential histological findings and clinical response after carbon ion radiotherapy for unresectable sarcoma. Clinical and Translational Radiation Oncology. 2,41-45, 2017
147. Hayashi K*, Niu X, Tang X, Singh VA, Asavamongkolkul A, Kawai A, Yamamoto N, Shirai T, Takeuchi A, Kimura A, Miwa S, Tsuchiya H. Experience of total scapular excision for musculoskeletal tumor and reconstruction in eastern Asian countries. Journal of Bone Oncology 9, 55-58, 2017
148. Miwa S, Nishida H, Tanzawa Y, Takeuchi A, Hayashi K, Yamamoto N, Mizukoshi E, Nakamoto Y, Kaneko S, Tsuchiya H. Phase 1/2 study of immunotherapy with dendritic cells pulsed with autologous tumor lysate in patients with refractory bone and soft tissue sarcoma. Cancer. 123(9):1576-1584,2017
149. Igarashi K, Li S, Han Q, Tan Y, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase. J Cell Biochem. 2017 Nov 16. doi: 10.1002/jcb.26527.
150. Miwa S, Shirai T, Yamamoto N, Hayashi K, Takeuchi A, Tada K, Kajino Y, Inatani H, Higuchi T, Abe K, Taniguchi Y, Tsuchiya H. Risk factors for postoperative deep infection in bone tumors. PLoS One. 2017 Nov 9;12(11):e0187438. doi: 10.1371/journal.pone.0187438. eCollection 2017.
151. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh AS, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2017 Mar 24;8(44):75874-75880. doi: 10.18632/oncotarget.16548. eCollection 2017 Sep 29.
152. Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Yamamoto N, Hayashi K, Kimura H, Nelson SD, Dry SM, Li Y, Singh AS, Miwa S, Odani A, Eilber FC, Tsuchiya H, Hoffman RM. A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenograft (PDOX). Oncotarget. 2017 Jun 28;8(38):63353-63359. doi: 10.18632/oncotarget.18806. eCollection 2017 Sep 8.
153. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Murakami T, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Hoffman RM. Effective Metabolic Targeting of Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models with Recombinant Methioninase. Anticancer Res. 2017 Sep;37(9):4807-4812.
154. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh AS, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines. Anticancer Res. 2017 Aug;37(8):4081-4084.
155. Higuchi T, Yamamoto N, Nishida H, Hayashi K, Takeuchi A, Kimura H, Miwa S, Inatani H, Shimozaki S, Kato T, Aoki Y, Abe K, Taniguchi Y, Tsuchiya H. Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen. Int Orthop. 2017 Oct;41(10):2189-2197. doi: 10.1007/s00264-017-3499-x. Epub 2017 Jun 1.
156. Rosario MS, Yamamoto N, Hayashi K, Takeuchi A, Kimura H, Miwa S, Higuchi T, Inatani H, Abe K, Taniguchi Y, Aiba H, Tsuchiya H. An unusual case of proximal humeral simple bone cyst in an adult from secondary cystic change. World J Surg Oncol. 2017 May 15;15(1):102. doi: 10.1186/s12957-017-1166-8.
157. Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell TA, Singh AS, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model. Cell Cycle. 2017 Jun 18;16(12):1164-1170. doi: 10.1080/15384101.2017.1317417. Epub 2017 May 11.
158. Zekry KM, Yamamoto N, Hayashi K, Takeuchi A, Higuchi T, Abe K, Taniguchi Y, Alkhooly AZAA, Abd-Elfattah AS, Fouly EH, Ahmed AR, Tsuchiya H. Intercalary frozen autograft for reconstruction of malignant bone and soft tissue tumours. Int Orthop. 2017 Jul;41(7):1481-1487. doi: 10.1007/s00264-017-3446-x. Epub 2017 Mar 25.
159. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Hoffman RM. Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. Anticancer Res. 2017 Mar;37(3):1005-1011.
160. Rosario M, Takeuchi A, Yamamoto N, Hayashi K, Miwa S, Higuchi T, Abe K, Taniguchi Y, Aiba H, Tanzawa Y, Murakami H, Tsuchiya H. Pathogenesis of Osteosclerotic Change Following Treatment with an Antibody Against RANKL for Giant Cell Tumour of the Bone. Anticancer Res. 2017 Feb;37(2):749-754.
161. Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. High Efficacy of Pazopanib on an Undifferentiated Spindle-Cell Sarcoma Resistant to First-Line Therapy Is Identified With a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model. J Cell Biochem. 2017 Sep;118(9):2739-2743. doi: 10.1002/jcb.25923. Epub 2017 Apr 25.
162. Inatani H, Yamamoto N, Hayashi K*, Kimura H, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Yamada S, Asai K, Otsuka T, Tsuchiya H. Do Mesenchymal Stem Cells Derived From Atypical Lipomatous Tumors Have Greater Differentiation Potency Than Cells From Normal Adipose Tissues? Clin Orthop Relat Res. 2017 Jun;475(6):1693-1701. doi: 10.1007/s11999-017-5259-z. Epub 2017 Feb 2.
163. Kosaka M, Nakase J, Hayashi K and Tsuchiya H: Adipose-Derived Regenerative Cells Promote Tendon-Bone Healing in a Rabbit Model. Arthrosc J Arthrosc Relat Surg 32: 851–859, 2016.
164. Miwa S, Toneri M, Igarashi K, Yano S, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H and Hoffman RM: Real-Time In Vivo Confocal Fluorescence Imaging of Prostate Cancer Bone-Marrow Micrometastasis Development at the Cellular Level in Nude Mice. J Cell Biochem 117: 2533–2537, 2016.
165. Abdelaal AHK, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Morsy AF, Kajino Y and Tsuchiya H: The linea aspera as a guide for femoral rotation after tumor resection: is it directly posterior? A technical note. J Orthop Traumatol 17: 255–259, 2016.
166. Abdelaal AHK, Yamamoto N, Hayashi K, Takeuchi A, Morsy AF, Miwa S, Kajino Y, Rubio DA and Tsuchiya H: Radiological assessment of the femoral bowing in Japanese population. SICOT-J 2: 2, 2016.
167. Shirai T, Tsuchiya H, Terauchi R, Tsuchida S, Mizoshiri N, Igarashi K, Miwa S, Takeuchi A, Kimura H, Hayashi K, Yamamoto N and Kubo T: The outcomes of reconstruction using frozen autograft combined with iodine-coated implants for malignant bone tumors: compared with non-coated implants. Jpn J Clin Oncol 46: 735–740, 2016.
168. Abe K, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Inatani H, Higuchi T, Taniguchi Y and Tsuchiya H: Balancing Prolonged Survival with QoL Using Low-dose Pazopanib Maintenance: A Comparison with the PALETTE Study. Anticancer Res 36: 2893–7, 2016.
169. Takeuchi A, Yamamoto N, Shirai T, Hayashi K, Miwa S, Munesue S, Yamamoto Y and Tsuchiya H: Clinical relevance of peroxisome proliferator-activated receptor-gamma expression in myxoid liposarcoma. BMC Cancer 16: 442, 2016.
170. Shimozaki S, Yamamoto N, Domoto T, Nishida H, Hayashi K, Kimura H, Takeuchi A, Miwa S, Igarashi K, Kato T, Aoki Y, Higuchi T, Hirose M, Hoffman RM, Minamoto T and Tsuchiya H: Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin. Oncotarget 7: 77038–77051, 2016.
171. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh A, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC and Hoffman RM: Patient-derived orthotopic xenograft (PDOX) mouse model of adult rhabdomyosarcoma invades and recurs after resection in contrast to the subcutaneous ectopic model. Cell Cycle 16: 91–94, 2017.
172. Kimura H, Yamamoto N, Shirai T, Nishida H, Hayashi K, Tanzawa Y, Takeuchi A, Miwa S and Tsuchiya H: Clinical Outcome of Reconstruction Using Frozen Autograft for a Humeral Bone Tumor. Anticancer Res 36: 6631–6636, 2016.
173. Rosario MS, Hayashi K*, Yamamoto N, Takeuchi A, Miwa S, Taniguchi Y and Tsuchiya H: Functional and radiological outcomes of a minimally invasive surgical approach to monostotic fibrous dysplasia. World J Surg Oncol 15: 1, 2017.
174. Inatani H, Yamamoto N, Hayashi K*, Kimura H, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Yamada S, Okamoto H, Otsuka T and Tsuchiya H: Surgical management of proximal fibular tumors: A report of 12 cases. J Bone Oncol 5: 163–166, 2016.
175. Rosario MS, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Inatani H, Higuchi T and Tsuchiya H: A case of infected schwannoma mimicking malignant tumor. World J Surg Oncol 14: 302, 2016.
176. Igarashi K, Yamamoto N, Hayashi K, Takeuchi A, Kimura H, Miwa S, Hoffman RM, Tsuchiya H. Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models. Anticancer Res. 36:4477-82, 2016
177. Takeuchi A, Yamamoto N, Hayashi K, Miwa S, Takahira M, Fukui K, Oikawa T, Tsuchiya H. Tenosynovial giant cell tumors in unusual locations detected by positron emission tomography imaging confused with malignant tumors: report of two cases. BMC Musculoskelet Disord. 17:180, 2016
178. Abe K, Takeuchi A, Yamamoto N, Hayashi K, Tada K, Miwa S, Inatani H, Aoki Y, Higuchi T, Tsuchiya H. Symptomatic small schwannoma is a risk factor for surgical complications and correlates with difficulty of enucleation. Springerplus. 4:751, 2015
179. Hayashi K*, Yamada S, Inatani H, Okamoto H, Takeuchi A, Nishida H, Yamamoto N, Tsuchiya H, Otsuka T. Salvage method for unplanned excision of soft tissue sarcoma: long-term results of second-look surgery following radio-hyperthermo-chemotherapy. Anticancer Res. 2015 ;35(1):493-8.
180. Subhadrabandhu S, Takeuchi A, Yamamoto N, Shirai T, Nishida H, Hayashi K, Miwa S and Tsuchiya H: Frozen Autograft-Prosthesis Composite Reconstruction in Malignant Bone Tumors. Orthopedics 38:e911–8, 2015
181. Kuroda K, Kabata T, Hayashi K, Maeda T, Kajino Y, Iwai S, Fujita K, Hasegawa K, Inoue D, Sugimoto N and Tsuchiya H: The paracrine effect of adipose-derived stem cells inhibits osteoarthritis progression. BMC Musculoskelet Disord 16: 236, 2015.
182. Shirai T, Tsuchiya H, Terauchi R, Tsuchida S, Mizoshiri N, Ikoma K, Fujiwara H, Miwa S, Kimura H, Takeuchi A, Hayashi K, Yamamoto N and Kubo T: Treatment of a Simple Bone Cyst Using a Cannulated Hydroxyapatite Pin. Medicine (Baltimore) 94: e1027, 2015.
183. Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Murakami T, Hayashi K, Yamamoto N, Fujiwara T, Tsuchiya H and Hoffman RM: Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging. Cell Cycle 14: 1932–7, 2015.
184. Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Matsumoto Y, Uehara F, Hiroshima Y, Murakami T, Hayashi K, Yamamoto N, Bouvet M, Fujiwara T, Tsuchiya H and Hoffman RM: Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging. Cell Cycle 14: 621–9, 2015.
185. Kimura H, Yamamoto N, Shirai T, Nishida H, Hayashi K, Tanzawa Y, Takeuchi A, Igarashi K, Inatani H, Shimozaki S, Kato T, Aoki Y, Higuchi T and Tsuchiya H: Efficacy of triplet regimen antiemetic therapy for chemotherapy-induced nausea and vomiting (CINV) in bone and soft tissue sarcoma patients receiving highly emetogenic chemotherapy, and an efficacy comparison of single-shot palonosetron and consecutive-da. Cancer Med 4: 333–41, 2015.
186. Igarashi K, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Odani A and Tsuchiya H: Effectiveness of two novel anionic and cationic platinum complexes in the treatment of osteosarcoma. Anticancer Agents Med Chem 15: 390–9, 2015.
187. Miwa S, Yano S, Yamamoto M, Matsumoto Y, Uehara F, Hiroshima Y, Toneri M, Murakami T, Kimura H, Hayashi K, Yamamoto N, Efimova E V, Tsuchiya H and Hoffman RM: Real-time fluorescence imaging of the DNA damage repair response during mitosis. J Cell Biochem 116: 661–6, 2015.
188. Aiba H, Hayashi K, Inatani H, Satoshi Y, Watanabe N, Sakurai H, Tsuchiya H, Otsuka T. Conservative treatment for patients with osteoid osteoma: a case series. Anticancer Res. 2014 Jul;34(7):3721-5.
189. Hayashi K*, Iwata S, Ogose A, Kawai A, Ueda T, Otsuka T, Tsuchiya H. Factors that influence functional outcome after total or subtotal scapulectomy: Japanese Musculoskeletal Oncology Group (JMOG) study. PLoS One. 2014 Jun 17;9(6):e100119.
190. Kimura H，Yamamoto N，Nishida H，Hayashi K，Takeuchi A，Nojima T，Ikeda H，Sawada-Kitamura S，Tsuchiya H.: Synovial sarcoma in knee joint，mimicking low-grade sarcoma confirmed by molecular detection of SYT gene split. Anticancer Res. 26: 3105-11，2014.
191. Nomura I，Watanabe K，Matsubara H，Hayashi K，Sugimoto N，Tsuchiya H: Uncultured autogenous adipose-derived regenerative cells promote bone formation during distraction osteogenesis in rats. Clin Orthop Relat Res. 12: 3798-806，2014.
192. Igarashi K，Yamamoto N，Shirai T，Hayashi K，Nishida H，Kimura H，Takeuchi A，Tsuchiya H: The long-term outcome following the use of frozen autograft treated with liquid nitrogen in the management of bone and soft-tissue sarcomas. Bone Joint J(B). 4: 555-61，2014.
193. Igarashi K，Yamamoto N，Shirai T，Nishida H，Hayashi K，Tanzawa Y，Kimura H，Takeuchi A，Miwa S，Inatani H，Shimozaki S，Kato T，Tsuchiya H: Late recurrence of osteosarcoma: a report of two cases. J Orthop Surg (Hong Kong). 3: 415-9，2014.
194. Fang X, Murakami H, Demura S, Hayashi K, Matsubara H, Kato S, Yoshioka K, Inoue K, Ota T, Shinmura K, Tsuchiya H. A novel method to apply osteogenic potential of adipose derived stem cells in orthopaedic surgery. PLoS One. 2014 Feb 19;9(2):e88874.
195. Miwa S，Zhang Y，Baek KE，Uehara F，Yano S，Yamamoto M，Hiroshima Y，Matsumoto Y，Kimura H，Hayashi K，Yamamoto N，Tsuchiya H，Bouvet M，Hoffman RM，Zhao M: Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R. Oncotarget. 5: 12849-61，2014.
196. Miwa S，Takeuchi A，Shirai T，Yamamoto N，Hayashi K，Nishida H，Kimura H，Igarashi K，Tsuchiya H: Outcomes and complications of reconstruction using tumour-bearing frozen autografts in patients with metastatic bone tumors. Anticancer Res. 34: 5569-77，2014.
197. Miwa S，Yano S，Zhang Y，Matsumoto Y，Uehara F，Yamamoto M，Hiroshima Y，Kimura H，Hayashi K，Yamamoto N，Bouvet M，Tsuchiya H，Hoffman RM，Zhao M: Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice. Oncotarget. 5: 7119-25，2014.
198. Miwa S，Hiroshima Y，Yano S，Zhang Y，Matsumoto Y，Uehara F，Yamamoto M，Kimura H，Hayashi K，Bouvet M，Tsuchiya H，Hoffman RM. Fluorescence-guided surgery improves outcome in an orthotopic osteosarcoma nude-mouse model. J Orthop Res. 32: 1596-601，2014.
199. Miwa S，Matsumoto Y，Hiroshima Y，Yano S，Uehara F，Yamamoto M，Zhang Y，Kimura H，Hayashi K，Yamamoto N，Bouvet M，Sugimoto N，Tsuchiya H，Hoffman RM: Fluorescence guided-surgery of prostate cancer bone metastasis. J Surg Res. 192: 124-33，2014.
200. Hayashi K*, Tsuchiya H, Yamamoto N, Shirai T, Nishida H, Takeuchi A, Kimura H, Miwa S, Inatani H, Okamoto H, Yamada S, Ikeda H, Sawada-Kitamura S, Nojima T, Ooi A, Otsuka T. Diagnosis and treatment of low-grade osteosarcoma: experience with nine cases. Int J Clin Oncol. 2014; 19(4):731-8
201. Shimozaki S, Yamamoto N, Shirai T, Nishida H, Hayashi K, Tanzawa Y, Kimura H, Takeuchi A, Igarashi K, Inatani H, Kato T, Tsuchiya H. Pedicle versus free frozen autograft for reconstruction in malignant bone and soft tissue tumors of the lower extremities. J Orthop Sci. 2014; 19(1):156-63
202. Miwa S, Takeuchi A, Ikeda H, Shirai T, Yamamoto N, Nishida H, Hayashi K, Tanzawa Y, Kimura H, Igarashi K, Tsuchiya H. Prognostic value of histological response to chemotherapy in osteosarcoma patients receiving tumor-bearing frozen autograft. PLoS One. 2013 Aug 15;8(8):e71362.
203. Miwa S, Yano S, Hiroshima Y, Tome Y, Uehara F, Mii S, Efimova EV, Kimura H, Hayashi K, Tsuchiya H, Hoffman RM. Imaging UVC-induced DNA damage response in models of minimal cancer. J Cell Biochem. 2013 Nov;114(11):2493-9.
204. Miwa S, Yano S, Tome Y, Sugimoto N, Hiroshima Y, Uehara F, Mii S, Kimura H, Hayashi K, Efimova EV, Fujiwara T, Tsuchiya H, Hoffman RM. Dynamic color-coded fluorescence imaging of the cell-cycle phase, mitosis, and apoptosis demonstrates how caffeine modulates cisplatinum efficacy. J Cell Biochem. 2013 Nov;114(11):2454-60.
205. Yamada S, Okamoto H, Sekiya I, Wada I, Kobayashi M, Goto H, Mizutani J, Nozaki M, Hayashi K, Murakami S, Murase A, Kawaguchi Y, Inatani H, Tatematsu N, Otsuka T. Anatomical basis of distally based anterolateral thigh flap. J Plast Surg Hand Surg. 48(3):197-200. 2013
206. Miwa S, Tome Y, Yano S, Hiroshima Y, Uehara F, Mii S, Kimura H, Hayashi K, Tsuchiya H, Bouvet M, Efimova EV, Hoffman RM. Single Cell Time-lapse Imaging of Focus Formation by the DNA Damage-Response Protein 53BP1 after UVC Irradiation of Human Pancreatic Cancer Cells. Anticancer Res. 33:1373-7, 2013
207. Miwa S, Nishida H, Tanzawa Y, Takata M, Takeuchi A, Yamamoto N, Shirai T, Hayashi K, Kimura H, Igarashi K, Mizukoshi E, Nakamoto Y, Kaneko S, Tsuchiya H. TNF-α and tumor lysate promote the maturation of dendritic cells for immunotherapy for advanced malignant bone and soft tissue tumors. PLoS One. 2012;7(12):e52926.
208. Watanabe K, Tsuchiya H, Yamamoto N, Shirai T, Nishida H, Hayashi K, Takeuchi A, Matsubara H, Nomura I. Over 10-year follow-up of functional outcome in patients with bone tumors reconstructed using distraction osteogenesis. J Orthop Sci. 2012
209. Miwa S, Sugimoto N, Yamamoto N, Shirai T, Nishida H, Hayashi K, Kimura H, Takeuchi A, Igarashi K, Yachie A, Tsuchiya H. Caffeine Induces Apoptosis of Osteosarcoma Cells by Inhibiting AKT/mTOR/S6K, NF-κB and MAPK Pathways. Anticancer Res. 32: 3643-9, 2012
210. Suganuma S, Tada K, Hayashi K, Takeuchi A, Sugimoto N, Ikeda K, Tsuchiya H. Uncultured adipose-derived regenerative cells promote peripheral nerve regeneration. J Orthop Sci. 18:145-151, 2012
211. Kimura H, Tome Y, Momiyama M, Hayashi K, Tsuchiya H, Bouvet M, Hoffman RM. Imaging the inhibition by anti-β1 integrin antibody of lung seeding of single osteosarcoma cells in live mice. Int J Cancer. 131 :2027-33,2012
212. Yamauchi K, Tome Y, Yamamoto N, Hayashi K, Kimura H, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. Color-coded Real-time Subcellular Fluorescence Imaging of the Interaction between Cancer and Host Cells in Live Mice. Anticancer Res. 32:39-43, 2012
213. Yamamoto N, Hayashi K, Tanzawa Y, Kimura H, Takeuchi A, Igarashi K, Inatani H, Shimozaki S, Kitamura S, Tsuchiya H. Treatment strategies for well-differentiated liposarcomas and therapeutic outcomes. Anticancer Res. 32: 1821-5, 2012
214. Miwa S, Taki J, Yamamoto N, Shirai T, Nishida H, Hayashi K, Tanzawa Y, Kimura H, Takeuchi A, Igarashi K, Ooi A, Tsuchiya H. A novel combined radiological method for evaluation of the response to chemotherapy for primary bone sarcoma. J Surg Oncol. 106:273-9, 2012
215. Kimura H, Tome Y, Momiyama M, Hayashi K, Tsuchiya H, Bouvet M, Hoffman RM. Imaging the inhibition by anti-β1 integrin antibody of lung seeding of single osteosarcoma cells in live mice. Int J Cancer. 2012 Nov 1;131(9):2027-33.
216. Hayashi K, Kimura H, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Hasegawa A, Bouvet M, Hoffman RM. Comparison of Cancer-Cell Seeding, Viability and Deformation in the Lung, Muscle and Liver, Visualized by Subcellular Real-time Imaging in the Live Mouse. Anticancer Res 31:3665-72, 2011
217. Takata M, Sugimoto N, Yamamoto N, Shirai T, Hayashi K, Nishida H, Tanzawa Y, Kimura H, Miwa S, Takeuchi A, Tsuchiya H. Activity of bone morphogenetic protein-7 after treatment at various temperatures: Freezing vs. pasteurization vs. allograft. Cryobiology 63:235-239, 2011
218. Karita M, Tsuchiya H, Yamamoto N, Shirai T, Hayashi K, Nishida H. Caffeine-potentiated chemotherapy for clear cell sarcoma: a report of five cases. Int J Clin Oncol 2011
219. Tsuchiya H, Takeuchi A, Yamamoto N, Shirai T, Hayashi K, Nishida H, Tomita K. High-grade undifferentiated pleomorphic sarcoma of pelvis treated with curettage and bone graft after complete remission following caffeine-potentiated chemotherapy. J Orthop Sci 16:476-81, 2011
220. Hayashi K*, Karita M, Yamamoto N, Shirai T, Nishida H, Takeuchi A, Kimura H, Miwa S, Tsuchiya H. Functional outcomes after total scapulectomy for malignant bone or soft tissue tumors in the shoulder girdle. Int J Clin Oncol 16:568-73, 2011
221. Tanzawa Y, Tsuchiya H, Shirai T, Nishida H, Hayashi K, Takeuchi A, Kawahara M, Tomita K. Potentiation of the antitumor effect of calcium phosphate cement containing anticancer drug and caffeine on rat osteosarcoma. J Orthop Sci 16:77-84, 2011
222. Miwa S, Shirai T, Taki J, Sumiya H, Nishida H, Hayashi K, Takeuchi A, Ooi A, Tsuchiya H. Use of (99m)Tc-MIBI scintigraphy in the evaluation of the response to chemotherapy for osteosarcoma: comparison with (201)Tl scintigraphy and angiography. Int J Clin Oncol 16:373-8, 2011
223. Nishida H, Shirai T, Hayashi K, Takeuchi A, Tanzawa Y, Mizokami A, Namiki M, Tsuchiya H. Cryotreatment against Metastatic Renal Cell Bone Tumour Reduced Multiple Lung Metastases. Anticancer Res 31:2927-30, 2011
224. Miwa S, Sugimoto N, Shirai T, Hayashi K, Nishida H, Ohnari I, Takeuchi A, Yachie A, Tsuchiya H. Caffeine activates tumor suppressor PTEN in sarcoma cells. Int J Oncol 39:465-72, 2011
225. Tsuchiya H, Nishida H, Srisawat P, Shirai T, Hayashi K, Takeuchi A, Yamamoto N, Tomita K. Pedicle frozen autograft reconstruction in malignant bone tumors. J Orthop Sci 15:340-9, 2010
226. Kimura H, Zhang L, Zhao M, Hayashi K, Tsuchiya H, Tomita K, Bouvet M, Wessels J, Hoffman RM. Targeted therapy of spinal cord glioma with a genetically modified Salmonella typhimurium. Cell Prolif 43:41-8, 2010
227. Kimura H, Lee C, Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. UV light killing efficacy of fluorescent protein-expressing cancer cells in vitro and in vivo. J Cell Biochem 110:1439-46, 2010
228. Kimura H, Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Bouvet M, Hoffman RM. Real-time imaging of single cancer-cell dynamics of lung metastasis. J Cell Biochem 109:58-64, 2010
229. Hasegawa A, Hayashi K, Kishimoto H, Yang M, Tofukuji S, Suzuki K, Nakajima H, Hoffman RM, Shirai M, Nakayama T. Color-coded real-time cellular imaging of lung T-lymphocyte accumulation and focus formation in a mouse asthma model. J Allergy Clin Immunol 125:461-468 e6, 2010
230. Yam C, Zhao M, Hayashi K, Ma H, Kishimoto H, McElroy M, Bouvet M, Hoffman RM. Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer. J Surg Res 164:248-55, 2010
231. Nagakura C, Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. Efficacy of a genetically-modified Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice. Anticancer Res 29:1873-8, 2009
232. Kimura H, Tsuchiya H, Shirai T, Nishida H, Hayashi K, Takeuchi A, Ohnari I, Tomita K. Caffeine-potentiated chemotherapy for metastatic osteosarcoma. J Orthop Sci 14:556-65, 2009
233. Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Bouvet M, Hoffman RM. Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhimurium. Cell Cycle 8:870-5, 2009
234. Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Hoffman RM. Cancer metastasis directly eradicated by targeted therapy with a modified Salmonella typhimurium. J Cell Biochem 106:992-8, 2009
235. Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Wessels J, Hoffman RM. A color-coded orthotopic nude-mouse treatment model of brain-metastatic paralyzing spinal cord cancer that induces angiogenesis and neurogenesis. Cell Prolif 42:75-82, 2009
236. Hayashi K, Upasani VV, Pawelek JB, Aubin CE, Labelle H, Lenke LG, Jackson R, Newton PO. Three-dimensional analysis of thoracic apical sagittal alignment in adolescent idiopathic scoliosis. Spine 34:792-7, 2009
237. Hayashi K, Tsuchiya H, Yamamoto N, Shirai T, Yamauchi K, Takeuchi A, Kawahara M, Miyamoto K, Tomita K. Impact of serum caffeine monitoring on adverse effects and chemotherapeutic responses to caffeine-potentiated chemotherapy for osteosarcoma. J Orthop Sci 14:253-8, 2009
238. Tome Y, Tsuchiya H, Hayashi K, Yamauchi K, Sugimoto N, Kanaya F, Tomita K, Hoffman RM. In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential. J Cell Biochem 108:362-7, 2009
239. Kishimoto H, Zhao M, Hayashi K, Urata Y, Tanaka N, Fujiwara T, Penman S, Hoffman RM. In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation. Proc Natl Acad Sci U S A 106:14514-7, 2009
240. Takeuchi A, Tsuchiya H, Shirai T, Hayashi K, Nishida H, Tomita K. Occlusive dressing for large soft tissue defects following soft tissue tumor excision. J Orthop Sci 14:385-90, 2009
241. Tanzawa Y, Tsuchiya H, Shirai T, Hayashi K, Yo Z, Tomita K. Histological examination of frozen autograft treated by liquid nitrogen removed after implantation. J Orthop Sci 14:761-8, 2009
242. McElroy M, Hayashi K, Garmy-Susini B, et al. Fluorescent LYVE-1 antibody to image dynamically lymphatic trafficking of cancer cells in vivo. J Surg Res 2009; 151:68-73.
243. Hayashi, K., Tsuchiya, H., Yamamoto, N., Takeuchi, A., and Tomita, K. Functional outcome in patients with osteosarcoma around the knee joint treated by minimized surgery. Int Orthop. 32(1):63-8. 2008
244. Yamauchi K, Yang M, Hayashi K, Jiang P, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Induction of cancer metastasis by cyclophosphamide pretreatment of host mice: an opposite effect of chemotherapy. Cancer Res 68:516-20, 2008
245. Hayashi, K., Yamauchi, K., Yamamoto, N., Tsuchiya, H., Tomita, K., Amoh, Y., Hoffman, R.M., and Bouvet, M. Dual color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma. J Surg Res. 140:165-70, 2007
246. Hayashi K, Jiang P, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Real-time imaging of tumor-cell shedding and trafficking in lymphatic channels. Cancer Res 67:8223-8, 2007
247. Takeuchi A, Tsuchiya H, Yamamoto N, Hayashi K, Yamauchi K, Kawahara M, Miyamoto K, Tomita K. Caffeine-potentiated chemotherapy for patients with high-grade soft tissue sarcoma: long-term clinical outcome. Anticancer Res. 2007 Sep-Oct;27(5B):3489-95.
248. Ji Y, Hayashi K, Amoh Y, Tsuji K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer. Anticancer Res. 2007 Mar-Apr;27(2):713-8.
249. Yamauchi K, Yang M, Hayashi K, Jiang P, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Imaging of nuclear dynamics during the cell cycle of cancer cells in live mice. Cell Cycle 6: 2706-2708, 2007.
250. Hayashi K, Tsuchiya H, Yamamoto N, Minato H, Tomita K. Histological examination of autoclaved bone removed 12 years after it was transplanted. J Orthop Sci 10:425-9, 2005